ROS-p53-cyclophilin-D signaling mediates salinomycin-induced glioma cell necrosis
نویسندگان
چکیده
منابع مشابه
ROS-p53-cyclophilin-D signaling mediates salinomycin-induced glioma cell necrosis
BACKGROUND The primary glioblastoma multiforme (GBM) is the most malignant form of astrocytic tumor with an average survival of approximately 12-14 months. The search for novel and more efficient chemo-agents against this disease is urgent. Salinomycin induces broad anti-cancer effects; however, its role in GBM and the underlying mechanism are not clear. RESULTS Here we found that salinomycin...
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ژورنال
عنوان ژورنال: Journal of Experimental & Clinical Cancer Research
سال: 2015
ISSN: 1756-9966
DOI: 10.1186/s13046-015-0174-1